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                           April 30, 2024

       Scott Hutton
       Chief Executive Officer
       Biodesix, Inc.
       919 West Dillon Rd.
       Louisville, Colorado 80027

                                                        Re: Biodesix, Inc.
                                                            Registration
Statement on Form S-1
                                                            Filed April 23,
2024
                                                            File No. 333-278881

       Dear Scott Hutton:

              This is to advise you that we have not reviewed and will not
review your registration
       statement.

               Please refer to Rules 460 and 461 regarding requests for
acceleration. We remind you
       that the company and its management are responsible for the accuracy and
adequacy of their
       disclosures, notwithstanding any review, comments, action or absence of
action by the staff.

                                                        Please contact Jane
Park at 202-551-7439 with any questions.




                           Sincerely,


                           Division of Corporation Finance

                           Office of Industrial Applications and

                           Services
       cc:                                              Samir Gandhi, Esq.