November 6, 2024 Scott Hutton President and Chief Executive Officer Biodesix, Inc. 919 West Dillon Road Louisville, Colorado 80027 Re: Biodesix, Inc. Registration Statement on Form S-3 Filed November 1, 2024 File No. 333-282939 Dear Scott Hutton: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Conlon Danberg at 202-551-4466 with any questions. Sincerely, Division of Corporation Finance Office of Industrial Applications and Services cc: Samir A. Gandhi, Esq.